solute carrier family 29 member 1; equilibrative nucleoside transporter 1; equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; equilibrative NBMPR-sensitive nucleoside transporter; nucleoside transporter, es-type (SLC29A1v ENT1)

Function

• mediates both influx & efflux of nucleosides across the membrane (equilibrative transporter)
• sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) & is Na+-independent
• higher affinity for adenosine
• inhibited by dipyridamole

Structure

• glycosylated
• belongs to the SLC29A transporter family

Compartment

membrane

Expression

• expressed in heart, brain, mammary gland, erythrocytes &
• placenta
• expressed in fetal liver & spleen

More general terms

• transmembrane 11 protein
• glycoprotein
• solute carrier family 29 (SLC29, SLC29A)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2030
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2030
• OMIM: https://mirror.omim.org/entry/602193
• UniProt: http://www.uniprot.org/uniprot/Q99808.html