transmembrane 4 L6 family member 4; intestine & liver tetraspan membrane protein; IL-TMP (TM4SF4 ILTMP)

Function

• regulates adhesive & proliferative status of intestinal epithelial cells
• can mediate density-dependent cell proliferation

Structure

• N-glycosylated; glycosylation is required for the growth inhibitory effect
• belongs to the L6 tetraspanin family

Compartment

membrane

Expression

jejunum & liver

More general terms

• tetraspanin (transmembrane-4-superprotein)
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7104
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7104
• OMIM: https://mirror.omim.org/entry/606567
• UniProt: http://www.uniprot.org/uniprot/P48230.html