uroplakin-2; UP2; uroplakin II; UPII (UPK2)

Function

• component of the asymmetric unit membrane (AUM)
• role in regulating the assembly of the AUM (putative)
• interacts with uroplakin-1a (UPK1A) (putative)

Structure

• belongs to the uroplakin-2 family

Compartment

• cell membrane; single-pass type 1 membrane protein (putative)
• heterodimer formation with UPK1A is a prerequisite to exit out of the endoplasmic reticulum (ER)

Expression

• expressed in ureter

More general terms

• uroplakin
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7379
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7379
• OMIM: https://mirror.omim.org/entry/611558
• UniProt: http://www.uniprot.org/uniprot/O00526.html