solute carrier family 36 member 1 (SLC36A1, proton-coupled amino acid transporter 1, PAT1, lysosomal amino acid transporter 1, LYAAT1)

Function

• neutral amino acid/proton symporter
• pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine & proline
• also recognize their D-enantiomers of neutral L-amino acids & some amino acid derivatives such as gamma-aminobutyric acid (GABA)

Structure

• belongs to the amino acid/polyamine transporter 2 family

Compartment

• cell membrane, lysosome membrane

Alternative splicing

named isoforms=2

More general terms

• solute carrier family 36 (SLC36, SLC36A)
• transmembrane 11e protein
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2063
• OMIM: https://mirror.omim.org/entry/606561
• UniProt: http://www.uniprot.org/uniprot/Q7Z2H8.html