semenogelin-2; semenogelin II; SGII (SEMG2)

Function

• role in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions & ejaculated spermatozoa
• semenogelin-2 is thought to form both the 71 kD polypeptide &, in its glycosylated form, the 76 kD polypeptide
• interacts with SERPINA5

Structure

belongs to the semenogelin family

Compartment

secreted

Expression

• expressed in seminal vesicles
• expressed, to a much lesser extent, in epididymis

More general terms

• secreted protein
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6407
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6407
• OMIM: https://mirror.omim.org/entry/182141
• UniProt: http://www.uniprot.org/uniprot/Q02383.html