collagen 6 alpha-6 (COL6A6)

Function

• collagen 6 acts as a cell-binding protein
• Pro at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains
• trimers composed of three different chains: COL6A1, COL6A2, & COL6A3 or COL6A5 or COL6A6 (probable)

Structure

• belongs to the type VI collagen family
• contains 9 VWFA domains

Compartment

• secreted, extracellular space, extracellular matrix (putative)
• deposed in the extracellular matrix of skeletal muscle (putative)

Alternative splicing

named isoforms=2

More general terms

• glycoprotein
• secreted protein

Component of

• collagen type-6

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=131873
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:131873
• UniProt: http://www.uniprot.org/uniprot/A6NMZ7.html