napsin-A; aspartyl protease 4; ASP4; Asp 4; napsin-1; TA01/TA02 (NAPSA, NAP1, NAPA)

Function

• may be involved in processing of pneumocyte surfactant precursors

Structure

belongs to the peptidase A1 family

Compartment

secreted (putative)

Expression

• expressed predominantly in adult lung (type II pneumocytes) & kidney & in fetal lung
• low expression in adult spleen
• very low expression in peripheral blood leukocytes

More general terms

• aspartic proteinase; carboxyl acid protease
• secreted protein
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9476
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9476
• OMIM: https://mirror.omim.org/entry/605631
• UniProt: http://www.uniprot.org/uniprot/O96009.html