semaphorin 3B, semaphorin V or semaphorin A

Function

• inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons

Structure

• belongs to the semaphorin family
• contains 1 Ig-like C2-type domain (immunoglobulin-like)
• contains 1 PSI domain
• contains 1 sema domain

Compartment

• secreted (putative)
• endoplasmic reticulum
• accumulates in the endoplasmic reticulum

Alternative splicing

• named isoforms=2

Expression

• expressed abundantly but differentially in a variety of neural & nonneural tissues

More general terms

• secreted protein
• glycoprotein
• semaphorin or semaphorin/collapsin family protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7869
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7869
• OMIM: https://mirror.omim.org/entry/601281
• UniProt: http://www.uniprot.org/uniprot/Q13214.html