cathepsin-Z (cathepsin P, cathepsin X, CTSZ)

Function

• carboxypeptidase
• carboxy-monopeptidase & carboxy-dipeptidase activity
• release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline
• weak endopeptidase activity

Structure

belongs to the peptidase C1 family

Compartment

lysosome

Expression

widely expressed

More general terms

• cathepsin
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1522
• OMIM: https://mirror.omim.org/entry/603169
• UniProt: http://www.uniprot.org/uniprot/Q9UBR2.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1522