ubiquitin-conjugating enzyme E2 O (ubiquitin-protein ligase O, ubiquitin carrier protein O, ubiquitin-conjugating enzyme E2 of 230 kD, E2-230K, UBE2O, KIAA1734)

Function

• ubiquitin conjugation, 2nd step
• catalyzes the covalent attachment of ubiquitin to other proteins

ATP + ubiquitin + protein lysine
              <-->
AMP + diphosphate + protein N-ubiquityllysine

Structure

• belongs to the ubiquitin-conjugating enzyme family

Expression

• predominantly expressed in skeletal muscle & heart

More general terms

• ubiquitin-conjugating protein E2 (ubiquitin carrier protein)
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9C0C9.html