Bodian copper-protargol stain

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Introduction

A silver stain using a silver proteinate complex (protargol) to identify neurofibrils. It is used to stain neurofibrillary tangles & senile plaques in Alzheimer's disease.

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References

  1. Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999
  2. Selkoe DJ. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev. 2001 Apr;81(2):741-66. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11274343