wings apart-like protein homolog (friend of EBNA2 protein, WAPAL, FOE, KIAA0261, WAPL)

Function

• may play a role in cell growth
• isoform 2 interacts with Epstein-Barr virus EBNA2

Structure

contains 1 WAPL domain

Compartment

isoform 2: nucleus

Alternative splicing

named isoforms=3

Expression

• isoform 2 is widely espressed with a high level in skeletal muscle & heart

Pathology

• isoform 1 is highly expressed in cervical cancer

More general terms

• phosphoprotein
• nuclear protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q7Z5K2.html