Filamin-A-interacting protein 1 (FILIP, FILIP1, KIAA1275)

Function

• controls start of neocortical cell migration from ventricular zone via filamin-A/F-actin axis
• induces degradation of filamin-A (putative)
• interacts with FLNA (putative)

Alternative splicing

named isoforms=3

Expression

• expressed in adult heart & brain > lung, skeletal muscle, ovary, testis, kidney, fetal brain > liver, pancreas, spleen, fetal liver
• within brain, moderate expression in amygdala & caudate nucleus

More general terms

• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/607307
• UniProt: http://www.uniprot.org/uniprot/Q7Z7B0.html