phosphoglucomutase-1; glucose phosphomutase 1; glucose-1-phosphate phosphodismutase (PGM 1, PGM1)

Function

• participates in both the breakdown & synthesis of glucose

alpha-D-glucose 1-phosphate <--> alpha-D-glucose 6-phosphate

Cofactor: binds 1 Mg+2 per subunit

Structure

• monomer
• belongs to the phosphohexose mutase family

Compartment

isoform 1: cytoplasm

Alternative splicing

named isoforms=2

Polymorphism

• any polymorphic variants of PGM1 exist
• 8 different alleles are known: PGM1*1+, PGM1*1-, PGM1*2+, PGM1*2-, PGM1*3+, PGM1*3-, PGM1*7+ & PGM1*7-

More general terms

• phosphoglucomutase or glucose phosphomutase
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/171900
• UniProt: http://www.uniprot.org/uniprot/P36871.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5236