brain phosphoglycerate mutase (phosphoglycerate mutase 1, phosphoglycerate mutase isozyme B, PGAM-B, PGAM1, BPG-dependent PGAM 1, PGAMA, CDABP0006)
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Function
- interconversion of 3-phosphoglycerate & 2-phosphoglycerate with 2,3-bisphosphoglycerate as a primer
- also synthase & phosphatase activity, albeit diminished
2-phospho-D-glycerate <--> 3-phospho-D-glycerate
3-phospho-D-glyceroyl phosphate <--> 2,3-bisphospho-D-glycerate 2,3-bisphospho-D-glycerate + H2O <--> 3-phospho-D-glycerate + phosphate
Structure
- homodimer
- belongs to the phosphoglycerate mutase family, BPG- dependent PGAM subfamily