mitotic kinesin-like protein 1 (kinesin-like protein KIF23, kinesin-like 5 protein, KNSL5, KIF23, MKLP1)

Function

• plus-end-directed motor enzyme that moves antiparallel microtubules in vitro.
• interacts with PRC1

Structure

• belongs to the kinesin-like protein family
• contains 1 kinesin-motor domain

Compartment

• nucleus
• localizes to the interzone of mitotic spindles
• undergoes redistribution during the cell cycle, moving from the nucleus to the spindle in early mitosis

Alternative splicing

named isoforms=2

More general terms

• kinesin family protein
• adenosine triphosphatase (ATPase)
• guanosine triphosphatase (GTPase)
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/605064
• UniProt: http://www.uniprot.org/uniprot/Q02241.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9493