glutathione S-transferase mu-1 (M1, GST1, GSH transferase HB subunit 4, GTH4, GSTM1A-1A, GST class-mu 1, GSTM1a-1a, GSTM1b-1b, HB subunit 4, GSTM1)

Function

• conjugation of reduced glutathione to a wide number of exogenous & endogenous hydrophobic electrophiles

RX + glutathione <--> HX + R-S-glutathione

Structure

• homodimer
• belongs to the GST superfamily, Mu family

Compartment

cytoplasm

Expression

liver

Polymorphism

• 2 alleles; GSTM1A & GSTM1B which differ in position 173

More general terms

• glutathione S-transferase mu
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P09488.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2944
• OMIM: https://mirror.omim.org/entry/138350
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2944