negative elongation factor B (NELF-B, cofactor of BRCA1, NELFB, COBRA1, KIAA1182)

Function

• essential component of the NELF complex,
• interacts with the first BRCT repeat of BRCA1

Structure

belongs to the NELF-B family

Compartment

nucleus

Expression

• widely expressed
• expressed in heart, brain, lung, placenta, liver, skeletal muscle, kidney & pancreas

More general terms

• protein subunit
• phosphoprotein

Component of

• negative elongation factor (NELF)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2592
• UniProt: http://www.uniprot.org/uniprot/Q8WX92.html