dolichol-phosphate mannosyltransferase 1 (dolichol-phosphate mannose synthase, dolichyl-phosphate beta-D-mannosyltransferase, mannose-P-dolichol synthase, MPD synthase, DPM synthase, dolichyl-phosphate mannosyltransferase 1 catalytic subunit, DPM1, dolichol-phosphate mannosyltransferase 1, dolichol-phosphate mannose synthase 1)

Function

• catalytic subunit of dolichol-phosphate mannosyltransferase

Structure

belongs to the glycosyltransferase 2 family

Compartment

endoplasmic reticulum

Pathology

• defects in DPM1 are the cause of congenital disorder of glycosylation type 1E

More general terms

• protein subunit
• phosphoprotein

Additional terms

• congenital disorder of glycosylation type 1E
• dolichol phosphate

Component of

• dolichyl-phosphate mannosyltransferase

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8813
• OMIM: https://mirror.omim.org/entry/603503
• OMIM: https://mirror.omim.org/entry/608799
• UniProt: http://www.uniprot.org/uniprot/O60762.html