eukaryotic initiation factor 3 subunit 10 (eukaryotic translation initiation factor 3 subunit A, eIF-3-theta, eIF3 p167, eIF3 p180, eIF3 p185, eIF3a, EIF3S10 KIAA0139)

Function

• binds to the 40S ribosome & promotes the binding of methionyl-tRNAi & mRNA
• may act as an adapter molecule between the translation initiation apparatus & the cytoskeleton

interacts with EIF3B & KRT7

phosphorylated

Structure

• belongs to the eIF-3 subunit A family
• contains 1 PCI domain

Compartment

cytoplasm

More general terms

• eukaryotic initiation factor subunit
• phosphoprotein

Component of

• eukaryotic initiation factor 3; ribosome dissociation factor (eIF3)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8661
• OMIM: https://mirror.omim.org/entry/602039
• UniProt: http://www.uniprot.org/uniprot/Q14152.html