eukaryotic initiation factor 3 subunit 3 (eukaryotic translation initiation factor 3 subunit H, eIF-3 gamma, eIF3 p40 subunit, eIF3h, EIF3S3, eiF3 p40)

Function

• binds to the 40S ribosome & promotes the binding of methionyl-tRNAi & mRNA
• associates with the p170 subunit of EIF3

Structure

• belongs to the peptidase M67 family
• contains 1 MPN (JAB/Mov34) domain

More general terms

• eukaryotic initiation factor subunit
• phosphoprotein

Component of

• eukaryotic initiation factor 3; ribosome dissociation factor (eIF3)

Database

• OMIM: https://mirror.omim.org/entry/603912
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8667
• UniProt: http://www.uniprot.org/uniprot/O15372.html