Peptide deformylase, mitochondrial (polypeptide deformylase, PDF, PDF1A)

Function

• removes the formyl group from the N-terminal Met of newly synthesized proteins (putative)

Formyl-L-methionyl peptide + H2O <--> formate + methionyl peptide

Cofactor: Binds 1 Fe+2 ion (putative)

Structure

belongs to the polypeptide deformylase family

Compartment

mitochondria (putative)

Expression

ubiquitous

More general terms

• mitochondrial protein
• carboxylase (carboxylic ester hydrolase)
• metalloprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9HBH1.html