Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3, Aminopeptidase P3, APP3) (XPNPEP3)

Function

• release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide

Cofactor: binds 2 Mn+2 per subunit (putative)

Structure

belongs to the peptidase M24B family

Alternative splicing

named isoforms=3

Expression

• isoform 1 & isoform 2 are widely expressed,
• isoform 1 is more abundant than isoform 2

More general terms

• Xaa-Pro aminopeptidase (XPNPEP)
• metalloprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9NQH7.html