synaptic vesicle membrane protein VAT-1 homolog (VAT1)

Function

• possesses ATPase activity (putative)
• role in Ca+2-regulated keratinocyte activation in epidermal repair mechanisms
• no effect on cell proliferation

Structure

• belongs to the Zn+2-containing alcohol dehydrogenase family, quinone oxidoreductase subfamily

Compartment

cytoplasm

Expression

• expressed in brain
• also expressed in glioblastoma cells
• increased expression in glioblastomas & on wounding, in basal keratinocytes (Ca+2-dependent)

More general terms

• metalloprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10493
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10493
• OMIM: https://mirror.omim.org/entry/604631
• UniProt: http://www.uniprot.org/uniprot/Q99536.html