40S ribosomal protein S27; metallopan-stimulin 1; MPS-1 (RPS27, MPS1)

Function

Cofactor: binds 1 Zn+2 per subunit (putative)

Structure

belongs to the ribosomal protein S27e family

Expression

• expressed in a wide variety of actively proliferating cells & tumor tissues

Notes

• originally thought to be a protein that could have played a role as a mediator of cellular proliferative responses to various growth factors & other environmental signals
• capable of specific binding to a cAMP response element in DNA

More general terms

• DNA-binding protein
• zinc finger protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P42677.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6232
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6232
• OMIM: https://mirror.omim.org/entry/603702