acetyl-coenzyme A synthetase 2-like, mitochondrial; acetyl-CoA ligase 2; acetyl-CoA synthetase 2; acyl-CoA synthetase short-chain family member 1 (ACSS1, ACAS2L, KIAA1846)

Function

• converts acetate to acetyl-CoA for oxidation in the TCA cycle

ATP + acetate + CoA <--> AMP + diphosphate + acetyl-CoA

Structure

• belongs to the ATP-dependent AMP-binding enzyme family

Compartment

mitochondrial matrix

Alternative splicing

named isoforms=2

More general terms

• acyl coenzyme-A [CoA] synthetase or acyl coenzyme-A [CoA] ligase
• mitochondrial protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9NUB1.html