agmatinase, mitochondrial (agmatine ureohydrolase, AUH, AGMAT)

Function

• amine & polyamine biosynthesis
• putrescine biosynthesis
• putrescine from agmatine (ADC route): step 1/1

agmatine + H2O  <--> putrescine + urea

Cofactor: Mn+2

Structure

belongs to the arginase family, agmatinase subfamily

Compartment

mitochondrion

Expression

• expressed in liver & kidney > skeletal muscle, fetal liver, brain, testis, skin, gastrointestinal tract

More general terms

• mitochondrial protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9BSE5.html