iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2, iron sulfur assembly protein IscA, hIscA, ISCA1, HBLD2, GK004)

Function

• role in assembly of mitochondrial iron-sulfur proteins
• role in binding of an intermediate of Fe/S cluster assembly

Structure

belongs to the hesB/iscA family

Compartment

mitochondria

Expression

• detected in cerebellum, kidney, heart

Pathology

• antibodies against HBLD2 are found in the serum of patients with Sjoegren syndrome, but also in healthy people

More general terms

• mitochondrial protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9BUE6.html