surfeit locus protein 1 (SURF1, SURF-1)

Function

• probably involved in the biogenesis of the COX complex

Structure

belongs to the SURF1 family

Compartment

• mitochondrial inner membrane
• multi-pass membrane protein (putative)

Alternative splicing

named isoforms=2

Pathology

• defects in SURF1 are a cause of Leigh syndrome

More general terms

• transmembrane 2 protein
• mitochondrial protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6834
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6834
• OMIM: https://mirror.omim.org/entry/185620
• OMIM: https://mirror.omim.org/entry/256000
• UniProt: http://www.uniprot.org/uniprot/Q15526.html