Ca+2-binding mitochondrial carrier protein Aralar1; mitochondrial aspartate glutamate carrier 1; solute carrier family 25 member 12 (SLC25A12, ARALAR1)

Function

• Ca+2-dependent mitochondrial aspartate & glutamate carrier
• may have a function in the urea cycle
• binds Ca+2

Structure

• belongs to the mitochondrial carrier family
• contains 4 EF-hand domains
• contains 3 solcar repeats

Compartment

mitochondrial inner membrane

Expression

• high levels in heart & skeletal muscle,
• low in brain
• very low in kidney2

More general terms

• Ca+2 binding protein
• mitochondrial protein
• transmembrane 6 protein
• solute carrier family 25 (SLC25, SLC25A)

Database

• OMIM: https://mirror.omim.org/entry/603667
• UniProt: http://www.uniprot.org/uniprot/O75746.html