neurolysin, mitochondrial; angiotensin-binding protein; microsomal endopeptidase; MEP; mitochondrial oligopeptidase M; neurotensin endopeptidase (NLN, AGTBP, KIAA1226)

Function

• hydrolyzes oligopeptides such as neurotensin, bradykinin & dynorphin A (putative)
• preferential cleavage in neurotensin: 10-Pro-|-Tyr-11

Cofactor: binds 1 Zn+2 per subunit (putative)

Structure

belongs to the peptidase M3 family

Compartment

• mitochondria intermembrane space
• cytoplasm (putative)

More general terms

• metalloprotease
• mitochondrial protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57486
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57486
• OMIM: https://mirror.omim.org/entry/611530
• UniProt: http://www.uniprot.org/uniprot/Q9BYT8.html