ladybird homeobox corepressor 1-like protein; LBX1 corepressor 1-like protein; functional smad-suppressing element on chromosome 18; fussel-18 (CORL2, FUSSEL18, SKOR2)

Function

• acts as a TGF-beta antagonist in the nervous system
• interacts with SMAD2 & SMAD3

Structure

belongs to the SKI family

Compartment

nucleus, cytoplasm

Alternative splicing

named isoforms=2

Expression

• expressed in cerebellum, spinal cord & testis
• isoform 2 is present in cerebellum (at protein level)

More general terms

• nuclear protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q2VWA4.html