MEF2-activating SAP transcriptional regulatory protein (MASTR, MAMSTR)

Function

• transcriptional coactivator
• stimulates transcriptional activity of MEF2C
• stimulates MYOD1 activity in part via MEF2, resulting in an enhancement of skeletal muscle differentiation (putative)
• interacts with MEF2C (putative)

Structure

contains 1 SAP domain

Compartment

nucleus (putative)

Alternative splicing

named isoforms=3

Expression

• expressed in skeletal muscle, brain, placenta & spleen

More general terms

• nuclear protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2843
• UniProt: http://www.uniprot.org/uniprot/Q6ZN01.html