DJ-1-binding protein; CAP-binding protein complex-interacting protein 1 (DJBP, EFCAB6, KIAA1672)

Function

• inhibits androgen receptor by recruiting histone deacetylase complex; protein DJ-1 antagonizes this inhibition by disrupting complex
• binds PARK7
• part of a ternary complex containing PARK7, DJBP & AR

Structure

contains 17 EF-hand domains

Compartment

nucleus

Alternative splicing

named isoforms=5

Expression

secifically expressed in the testis

More general terms

• Ca+2 binding protein
• nuclear protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q5THR3.html