26S proteasome complex subunit DSS1 (split hand/foot malformation type 1 protein, deleted in split hand/split foot protein 1, split hand/foot deleted protein 1, SHFM1, DSS1, SHFDG1)

Function

• subunit of the 26S proteasome
• interacts with the C-terminal of BRCA2

Expression

expressed in limb bud, craniofacial primordia, skin

Pathology

• defects in DSS1 may be associated with split hand/split foot malformation

More general terms

• protein subunit

Component of

• 26S proteasome

Database

• OMIM: https://mirror.omim.org/entry/601285
• UniProt: http://www.uniprot.org/uniprot/P60896.html