phenylalanyl-tRNA synthetase alpha chain; phenylalanine-tRNA ligase alpha chain; PheRS; CML33 (FARSLA, FARS, FARSA, FARSL)

Function

• subunit of tetramer of two alpha & two beta chains

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe)

Structure

• belongs to the class-II aminoacyl-tRNA synthetase family, Phe-tRNA synthetase alpha subunit type 2 subfamily

Compartment

cytoplasm

Alternative splicing

named isoforms=2

More general terms

• protein subunit
• phosphoprotein

Component of

• phenylalanyl-tRNA synthetase (phenylalanine-tRNA ligase)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2193
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2193
• OMIM: https://mirror.omim.org/entry/602918
• UniProt: http://www.uniprot.org/uniprot/Q9Y285.html