peptide chain release factor subunit 1 (ERF1, TB3-1,eukaryotic release factor 1, protein Cl1, ETF1 RF1, SUP45L1)

Function

• directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG & UGA

Structure

• heterodimer of two subunits, one of which binds GTP
• belongs to the eukaryotic release factor 1 family

Compartment

cytoplasm

More general terms

• protein subunit

Database

• UniProt: http://www.uniprot.org/uniprot/P62495.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2107
• OMIM: https://mirror.omim.org/entry/600285