splicing factor 3B subunit 4 (spliceosome associated protein 49, SAP 49, SF3b50, pre-mRNA splicing factor SF3b 49 kD subunit, STAF130, SF3B3, KIAA0017)

Function

• subunit of the splicing factor SF3B
• belongs also to the minor U12-dependent spliceosome
• SF3B4 interacts directly with SF3B2

Structure

• belongs to the SF3B4 family
• contains 2 RRM domain (RNA recognition motif)s

Compartment

nucleus (putative)

More general terms

• splicing factor; snRNP-associated protein
• protein subunit

Component of

• splicing factor 3B (SF3B)

Database

• OMIM: https://mirror.omim.org/entry/605593
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1026
• UniProt: http://www.uniprot.org/uniprot/Q15427.html