mitochondrial import inner membrane translocase subunit TIM14 (DnaJ homolog subfamily C member 19, DNAJC19, TIM14, TIMM14)

Function

• probable component of the PAM complex (ATP-dependent)
• may act as a co-chaperone that stimulate the ATP-dependent activity (putative)

Structure

• belongs to the TIM14 family
• contains 1 J domain

Compartment

• mitochondrial inner membrane

Expression

ubiquitously expressed

Pathology

• defects in DNAJC19 are the cause of 3-methylglutaconic aciduria type 5

More general terms

• protein subunit
• mitochondrial membrane protein
• DNAJ homolog subfamily C

Component of

• mitochondrial import inner membrane translocase subunit (TIM, translocase of inner mitochondrial membrane, mitochondrial protein importer)
• PAM complex

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1311
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6445
• UniProt: http://www.uniprot.org/uniprot/Q96DA6.html