dynactin subunit 4 (dynactin subunit p62, DCTN4)

Function

• dual role in dynein targeting & in ACTR1A/Arp1 subunit of dynactin pointed-end capping (putative)
• role in ACTR1A pointed-end binding & in linking dynein & dynactin to the cortical cytoskeleton (putative)
• member of the pointed-end complex of the dynactin shoulder complex
• binds directly to the ACTR1A subunit of dynactin

Structure

belongs to the dynactin subunit 4 family

Compartment

• cytoplasm, centrosome
• punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin
• may be targeted to the nucleus with very high expression

More general terms

• protein subunit

Component of

• dynactin

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5116
• UniProt: http://www.uniprot.org/uniprot/Q9UJW0.html