hyccin (protein FAM126A, down-regulated by CTNNB1 protein A, FAM126A, DRCTNNB1A)

Function

• may have a role in the beta-catenin/Lef signaling pathway
• role in the process of myelination of the nervous system

Structure

belongs to the FAM126 family

Compartment

cytoplasm, membrane

Alternative splicing

named isoforms=2

Expression

• widely expressed
• highest levels in heart, brain, placenta, spleen & testis
• down-regulated by beta-catenin

Pathology

• defects in FAM126A are the cause of hypomyelination with congenital cataract

More general terms

• other protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9BYI3.html