peptidylprolyl isomerase-like 5 (LRR-repeat protein 1, LRR-1, 4-1BB-mediated-signaling molecule, 4-1BBlrr, PPIL5, LRR1)

Function

• may negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NF-kappa-B & JNK1
• interacts with the cytoplasmic domain of TNFRSF9

Structure

contains 5 LRR repeats (leucine-rich repeats)

Alternative splicing

named isoforms=2

Expression

• ubiquitous
• maximal expression was seen in the heart & skeletal muscle & minimal expression seen in the kidney

More general terms

• other protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q96L50.html