oxidative stress induced growth inhibitor 1 (pregnancy-induced growth inhibitor OKL38; huOKL38; ovary, kidney & liver protein 38; OSGIN1; OKL38)

Function

• regulates differentiation & proliferation of normal cells through regulation of cell death

Structure

• belongs to the OKL38 family

Alternative splicing

named isoforms=3

Expression

• ubiquitous
• highest expression in ovary, testis, kidney, liver
• induced by pregnancy

Pathology

• loss of OSGIN1 protein disturbs balance between cell growth, differentiation, & cell death in normal tissue, resulting in tumorigenesis

More general terms

• other protein

Database

• OMIM: https://mirror.omim.org/entry/607975
• UniProt: http://www.uniprot.org/uniprot/Q9UJX0.html