FXYD domain-containing ion transport regulator 3 (Cl- conductance inducer protein Mat-8, mammary tumor 8 kD protein, phospholemman-like, FXYD3, MAT8, PLML)

Function

• induces a hyperpolarization-activated Cl- current when expressed in Xenopus oocytes
• activates endogenous oocyte channels (putative)

Compartment

membrane

Pathology

• expressed in a subset of human breast tumors
• marker of a cell type preferentially transformed by neu or ras oncoprotein

More general terms

• other protein

Database

• OMIM: https://mirror.omim.org/entry/604996
• UniProt: http://www.uniprot.org/uniprot/Q14802.html