protein FAM107A (down-regulated in renal cell carcinoma 1, protein TU3A, FAM107A, DRR1, TU3A)
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Structure
- belongs to the FAM107 family
Compartment
Alternative splicing
named isoforms=2
Expression
widely expressed in normal tissues
Pathology
- expression is diminished or absent in several cancer cell lines
- when transfected into cell lines in which it is not expressed, suppresses cell growth
- role in tumor development ?