neurogenic differentiation factor 6 (NeuroD6)

Function

• activates E box-dependent transcription in association with TCF3/E47
• trans-acting factor involved in development & maintenance of nervous system
• transactivates promoter of its own gene
• efficient DNA binding requires dimerization with another bHLH protein

Structure

• contains 1 basic helix-loop-helix domain (bHLH)

Compartment

nucleus (probable)

More general terms

• other protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q96NK8.html