Tob2 protein; protein Tob4; transducer of erbB-2 2 (TOB2, KIAA1663, TOB4, TROB2)

Function

• anti-proliferative protein
• inhibits cell cycle progression from the G0/G1 to S phases
• associates with CAF1

Structure

belongs to the BTG family

Compartment

cytoplasm

Expression

ubiquitous

More general terms

• phosphoprotein

Additional terms

• receptor tyrosine-protein kinase erbB-2; p185erbB2; C-erbB-2; NEU proto-oncogene; tyrosine kinase-type cell surface receptor HER2; MLN 19; CD340 (ERBB2, HER2, NEU, NGL)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10766
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10766
• OMIM: https://mirror.omim.org/entry/607396
• UniProt: http://www.uniprot.org/uniprot/Q14106.html