surfeit locus protein 5; mediator of RNA polymerase II transcription subunit 22; mediator complex subunit 22; Surf-5 (MED22, SURF5)

Function

• component of the mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase 2-dependent genes

Structure

belongs to the mediator complex subunit 22 family

Compartment

nucleus (probable)

Alternative splicing

named isoforms=2; Surf5B, Surf5A

More general terms

• nuclear protein

Component of

• mediator complex (mediator of RNA polymerase 2 transcription)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6837
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6837
• OMIM: https://mirror.omim.org/entry/185641
• UniProt: http://www.uniprot.org/uniprot/Q15528.html