Glioma pathogenesis-related protein 1; GliPR 1; protein RTVP-1 (GLIPR1, GLIPR, RTVP1)
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Structure
- belongs to the CRISP family
Compartment
- membrane (potential)
Expression
- ubiquitously expressed with high levels in lung & kidney & low levels in heart & liver[3]
- highly expressed in cell lines derived from nervous system tumors arising from glia
- low or absent in non-glial-derived nervous system tumor cell lines
- also found in fetal kidney
- expressed only in brain tumor glioblastoma multiforme & astrocytoma & not in other nervous system tumors or normal fetal or adult tissues[4]
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/P48060.html
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=11010
- ↑ 3.0 3.1 Rich T et al RTVP-1, a novel human gene with sequence similarity to genes of diverse species, is expressed in tumor cell lines of glial but not neuronal origin. Gene. 1996 Nov 21;180(1-2):125-30. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8973356
- ↑ 4.0 4.1 Murphy EV et al The human glioma pathogenesis-related protein is structurally related to plant pathogenesis-related proteins and its gene is expressed specifically in brain tumors. Gene. 1995 Jun 14;159(1):131-5. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7607567