eukaryotic elongation factor 2 kinase; eEF-2 kinase; eEF-2K; EC=2.7.11.20; Ca+2/calmodulin-dependent eukaryotic elongation factor 2 kinase (EEF2K)

Function

• phosphorylates eukaryotic elongation factor-2
• binds calmodulin (putative)
• Ca+2/calmodulin-dependent intramolecular autophosphorylation results in becoming partially Ca+2/calmodulin-independent (putative)

Structure

• monomer or homodimer (putative)
• belongs to the protein kinase superfamily, alpha-type protein kinase family
• contains 1 alpha-type protein kinase domain

More general terms

• serine/threonine kinase

Additional terms

• eukaryotic elongation factor 2 (EF2, EEF2)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=29904
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:29904
• OMIM: https://mirror.omim.org/entry/606968
• UniProt: http://www.uniprot.org/uniprot/O00418.html